| 广东省屏障设施小鼠群中小鼠肝炎病毒感染情况 |
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| 引用本文： | 刘香梅,张钰,赵维波,吴玉娥,王静,张谱华.广东省屏障设施小鼠群中小鼠肝炎病毒感染情况[J].中国实验动物学杂志,2009(10):72-74. |
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| 作者姓名： | 刘香梅 张钰 赵维波 吴玉娥 王静 张谱华 |
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| 作者单位： | 广东省实验动物监测所,广州510260 |
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| 基金项目： | 广东省实验动物重点实验室（2007B060101002）. |
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| 摘 要： | 目的了解我省屏障设施小鼠群中小鼠肝炎病毒（MHV）感染情况。方法收集2003-2007年实验动物小鼠血清样品的监测数据,并对MHV感染情况有关数据进行分析。结果在6个屏障设施内抽检小鼠,5个屏障设施内抽检的样品检出MHV毒抗体阳性,检出率分别为1.4%,2.4%,2.8%,2.6%,13.2%。品系方面主要分布在BALB/c,BALB/c-nu/nu,NIH三个品系,检出率分别为3.6%,14%,7.1%。结论屏障设施小鼠群中小鼠肝炎病毒感染较为普遍。
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| 关 键 词： | 小鼠 肝炎病毒 屏障设施 |
Investigation on Mouse Hepatitis Virus Infection of Laboratory Mouse in Guangdong Province |
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| LIU Xiang-mei,ZHANG Yu,ZHAO Wei-bo,WU Yu-e,WANG Jing,ZHANG Pu-hua.Investigation on Mouse Hepatitis Virus Infection of Laboratory Mouse in Guangdong Province[J].Chinese Journal of Laboratory Animal Science,2009(10):72-74. |
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| Authors: | LIU Xiang-mei ZHANG Yu ZHAO Wei-bo WU Yu-e WANG Jing ZHANG Pu-hua |
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| Institution: | (Guangdong Laboratory Animal Monitoring Institute, Guangzhou 510260, China) |
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| Abstract: | Objective To define infection of mouse hepatitis virus（MHV） of laboratory mouse.Methods The monitor data of serum samples on MHV infection was collected for analysis from 2003 to 2007.Results 5 of 6 barrier animal facilities were detected MHV antibody positive,positive rate were 1.4%,2.4%,2.8%,2.6% respectively,as well as 3.6% in BALB/c,14% in BALB/c-nu/nu and 7.1% in NIH.Conclusion MHV infection on laboratory mouse in barrier facilities occur more commonly than other viruses. |
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| Keywords: | Mouse Hepatitis virus Barrier facility |
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