|
|||||
|
|
Sarcoptes scabiei: Specific immune response to sarcoptic mange in the Iberian ibex Capra pyrenaica depends on previous exposure and sex |
|
| Authors: | Mathieu Sarasa Luisa Rambozzi Pier G Meneguz José-Enrique Granados Paulino Fandos Georges Gonzalez Jesús M Pérez |
| Institution: | a Departamento de Biología Animal, Biología Vegetal y Ecología, Facultad de Ciencias Experimentales, Universidad de Jaén. Campus las Lagunillas, s.n., E-23071 Jaén, Spain b Laboratoire Comportement et Ecologie de la Faune Sauvage, Institut National de la Recherche Agronomique, BP 52627, F-31326 Castanet-Tolosan Cedex, France c Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Università degli Studi di Torino, V. Leonardo da Vinci 44, IT-10095 Grugliasco (TO), Italy d Servei d’Ecopatologia de Fauna Salvatge, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Spain e Espacio Natural Sierra Nevada, Carretera Antigua de Sierra Nevada, km. 7. E-18071 Pinos Genil, Granada, Spain f Laboratorio PROLAB. Carrera, 51. E-23600 Martos, Jaén, Spain g EGMASA, Avenida Johan G. Gutenberg, s.n., Isla de la Cartuja, E-41092 Sevilla, Spain h Estación Biológica de Doñana (C.S.I.C). Avenida Americo Vespucio, s.n., Isla de la Cartuja, E-41092 Sevilla, Spain |
| Abstract: | Host acquired immunity is a critical factor that conditions the survival of parasites. Nevertheless, there is a shortage of data concerning inter-individual immunological inequalities in wild mammals. Sarcoptic mange is a widespread parasitosis that severely affects mammals such as the Iberian ibex (Capra pyrenaica). Despite some work on the subject, the immune response to sarcoptic mange infestation is still a complex and poorly understood phenomenon. To improve knowledge of the host-Sarcoptes immunological interaction, 18 Iberian ibexes were experimentally infested. IgG levels were assessed using ELISA to test for potential factors determining the specific immune response to infestation. Previous exposure and sex appeared to affect the IgG response to infestation and our results suggest a sex-biased immunomodulation. We discuss the immunological pattern of host-Sarcoptes interactions and also suggest further lines of work that may improve the understanding of immunological interactions of host-Sarcoptes systems. |
| Keywords: | Capra pyrenaica Immunity Inter-individual variability Sarcoptes scabiei Ungulate |
| 本文献已被 ScienceDirect 等数据库收录！ | |