Current knowledge of the pre-autophagosomal structure (PAS) |
| |
| Authors: | Kuninori Suzuki |
| |
| Institution: | Advanced Research Organization, Integrated Research Institute, Tokyo Institute of Technology, 4259-S2-12 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan |
| |
| Abstract: | Autophagy is a system for degradation of bulk cellular components in lytic compartments, vacuoles, or lysosomes when eukaryotic cells face with nutrient starvation. In this review, we focus on the pre-autophagosomal structure (PAS), a functional entity responsible for autophagosome formation in Saccharomyces cerevisiae, and discuss its relevance to autophagy in mammalian cells. |
| |
| Keywords: | Autophagy Autophagosome Pre-autophagosomal structure Protein degradation Atg proteins |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
