Increased radiosensitivity after irradiation of lymphocytes low adaptive doses |
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Authors: | Pelevina I I Aleshchenko A V Gotlib V Ia Kudriashova O V Noskin L A Semenova L P Sotnikova E N Serebrianyĭ A M |
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Affiliation: | Semenov Institute of Chemical Physics, Russion Academy of Sciences, Moscow, 117977 Russia. |
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Abstract: | The variability of blood lymphocyte reaction on the adaptive irradiation (0.05 Gy at first, then 1.0 Gy 5 h later) was investigated by micronuclei assay. Blood samples were obtained from 700 children. It was shown that in all groups studied there were children with enhanced radiosensitivity ("radiosensitivity syndrome"-RS) after exposure to adaptive low dose of radiation. The radiosensitivity syndrome occurred more often in groups of ill children; part of them was characterized by the enhanced blood content of immunoglobulin E, enhanced level of T helpers and T suppressors. A high spontaneous level of lymphocytes with micronucleus is a factor of radiosensitivity formation. The possible factors resulted in radiosensitivity syndrome are discussed. |
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