Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells |
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| Authors: | Kai Cai Natasha C. Lucki Marion B. Sewer |
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| Affiliation: | Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA |
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| Abstract: | |
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| Keywords: | DGK, diacylglycerol kinase PA, phosphatidic acid SF1, steroidogenic factor 1 CYP, cytochrome P450 DAG, diacylglycerol DHEA, dehydroepiandrosterone StAR, steroidogenic acute regulatory protein ASAH1, acid ceramidase SPHK, sphingosine kinase PLD, phospholipase D LPIN, lipin SREBP, sterol regulatory element binding protein LDLR, low density lipoprotein receptor |
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