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Blocking mPTP on Neural Stem Cells and Activating the Nicotinic Acetylcholine Receptor α7 Subunit on Microglia Attenuate Aβ-Induced Neurotoxicity on Neural Stem Cells
Authors:Chen  Qingzhuang  Wang  Kewan  Jiang  Deqi  Wang  Yan  Xiao  Xiaodan  Zhu  Ning  Li  Mingxing  Jia  Siyuan  Wang  Yong
Institution:1.Department of Pharmacy, Southern Medical University, Zhujiang Hospital, Guangzhou, China
;2.Department of Clinical Pharmacy, Guangzhou Hospital of Integrated Traditional and Western Medicine, Guangzhou, China
;3.Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, China
;
Abstract:Neurochemical Research - β-Amyloid (Aβ) can stimulate microglia to release a variety of proinflammatory cytokines and induce neurotoxicity. Nicotine has been reported to inhibit...
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