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CREam of cytokinin signalling: receptor identified.
Authors:T Schmülling
Institution:2. Indian Institute of integrated Medicine (IIIM) Srinagar, Srinagar, India;3. Amity Institute of Pharmacy, Amity University, Noida, India;4. Department of Botany, University of Kashmir, Srinagar, India;1. State Key Laboratory of Tree Genetics Breeding, Northeast Forestry University, 26 Hexing Road, Harbin 150040, China;2. College of Life Science and Technology, Heilongjiang Bayi Agricultural University, Daqing 163319, China;3. Forest Biotechnology Group, Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC 27695, United States;4. Alkali Soil Natural Environmental Science Center, Northeast Forestry University, Key Laboratory of Saline-alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, Harbin 150040, China
Abstract:Cytokinins play a central role in the regulation of plant cell division and numerous developmental processes. Pleiotropic effects have made studies of this hormone difficult, and cytokinin signalling pathways have long remained elusive. The recent identification of CRE1 (a histidine kinase identical to AHK4 and WOL) as the cytokinin receptor of Arabidopsis thaliana is a landmark in cytokinin research. Mutations have been identified in CRE1, and the phenotype of loss-of-function mutations sheds new light on the role of cytokinins in plant development. This article describes the experimental paths leading to receptor identification and the current interpretation of its function.
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