In vitro antibacterial activity of laboratory grown culture of Spirulina platensis |
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Authors: | P Kaushik Abhishek Chauhan |
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Institution: | (1) Department of Botany and Microbiology, Gurukul Kangri University, Hardwar, 249 404 Uttarakhand, India |
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Abstract: | The hexane, ethyl acetate, dichloromethane, methanol extracts and spent media (extracellular substances) were tested in vitro
for their antibacterial activity for which one Gram-positive bacterium (Staphylococcus aureus) and four Gram-negative bacteria
(Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Klebsiella pneumoniae) were used as test organisms. The methanol
extract showed more potent activity than other organic extracts, spent medium of the culture exhibited little activity against
E. coli only. No inhibitory effect was found against Klebsiella pneumoniae.The broth microdilution assay gave minimum inhibitory
concentrations (MIC) values ranging from 1 to 512 μg/ml. The MIC of methanol extract against S. aureus and E. coli were 128
μg/ml and 256 μg/ml, respectively. |
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Keywords: | Antibacterial activity Spirulina platensis Minimum inhibitory concentration |
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