| 昆虫毒蕈碱型乙酰胆碱受体的研究进展 |
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| 引用本文： | 李建芳,成杨,陆永跃,齐易香.昆虫毒蕈碱型乙酰胆碱受体的研究进展[J].环境昆虫学报,2021,43(1):66-78. |
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| 作者姓名： | 李建芳 成杨 陆永跃 齐易香 |
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| 作者单位： | 华南农业大学植物保护学院昆虫学系,广州510642 |
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| 基金项目： | 国家自然科学基金项目（31801741）；农业农村部农作物病虫鼠害疫情综合防控项目（15206036） |
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| 摘 要： | 毒蕈碱型乙酰胆碱受体(Muscarinic Acetylcholine Receptors,mAChRs)是昆虫神经系统中一类重要的G蛋白偶联受体.昆虫mAChRs可以分为A、B、C型三大类,它们通过偶联不同的G蛋白激活不同的第二信使,完成信号转导过程,从而发挥其功能.mAChRs参与调控昆虫多种生理反应和行为过程,如...
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| 关 键 词： | 昆虫 毒蕈碱乙酰胆碱受体 药理学 生理功能 |
Advances in insect muscarinic acetylcholine receptors |
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| LI Jian-Fang,CHENG Yang,LU Yong-Yue,QI Yi-Xiang.Advances in insect muscarinic acetylcholine receptors[J].Journal of Environmental Entomology,2021,43(1):66-78. |
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| Authors: | LI Jian-Fang CHENG Yang LU Yong-Yue QI Yi-Xiang |
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| Institution: | Department of Entomology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China |
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| Abstract: | Muscarinic acetylcholine receptors (mAChRs), are mainly G-protein-coupled receptors in insect nervous system. There are three subtypes of insect mAChRs, namely mAChR-A, mAChR-B and mAChR-C. These receptors initiate different second-messenger pathways via coupling different G-proteins. mAChRs are involved in the regulation of a variety of physiological responses and behavioral processes in insects, such as growth and development, locomotion, stridulation, olfaction, learning and memory. Insect mAChRs are important potential targets of insecticides. In this paper, the recent advances in the tissue distribution, signal transduction, pharmacological properties and physiological roles of insect mAChRs were reviewed, which would provide a reference for further study on those receptors. |
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| Keywords: | Insect muscarinic acetylcholine receptor pharmacology physiological function |
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