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Cytochrome p450 conformational diversity
Authors:Stout C D
Affiliation:Department of Molecular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Abstract:Cytochrome P450s display a remarkable range of conformations in parallel with activity toward a great diversity of substrates. This aspect of P450s now extends to include the dynamic behavior of the protein, as shown by recent crystal structures of Cyp51.
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