|
|||||
|
|
Cycloartane-type glycosides from Astragalus amblolepis |
|
| Authors: | Emre Polat Angela Perrone Erdal Bedir |
| Affiliation: | a Ege University, Faculty of Science, Department of Chemistry, Bornova, 35100 ?zmir, Turkey b Salerno University, Department of Pharmaceutical Sciences, 84084 Fisciano, Salerno, Italy c Ege University, Faculty of Engineering, Department of Bioengineering, Bornova, 35100 ?zmir, Turkey |
| Abstract: | Five cycloartane-type triterpene glycosides were isolated from the methanol extract of the roots of Astragalus amblolepis Fischer along with one known saponin, 3-O-β-D-xylopyranosyl-16-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane. Structures of the compounds were established as 3-O-β-D-xylopyranosyl-25-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane, 3-O-[β-D-glucuronopyranosyl-(1 → 2)-β-D-xylopyranosyl]-25-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane, 3-O-β-D-xylopyranosyl-24,25-di-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane, 6-O-α-L-rhamnopyranosyl-16,24-di-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane, 6-O-α-L-rhamnopyranosyl-16,25-di-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxy-cycloartane by using 1D and 2D-NMR techniques and mass spectrometry. To the best of our knowledge, the glucuronic acid moiety in cycloartanes is reported for the first time. |
| Keywords: | Astragalus amblolepis Leguminosae Cycloartane Glucuronic acid Saponin |
| 本文献已被 ScienceDirect 等数据库收录！ | |