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Polyphenols isolated from antiradical extracts of Mallotus metcalfianus |
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| Authors: | Céline Rivière Van Nguyen Thi Hong Luc Pieters Yvan Vander Heyden Joëlle Quetin-Leclercq |
| Institution: | a Université Catholique de Louvain, Louvain Drug Research Institute, CHAM Unit, UCL 7230, Avenue E. Mounier 7, B-1200 Brussels, Belgium b Institute of Natural Products Chemistry, Vietnamese Academy of Science and Technology, 18 Hoang Quoc Viet Road, Nghia Do Cau Giay, Hanoi, Viet Nam c Vrije Universiteit Brussel, Department of Analytical Chemistry and Pharmaceutical Technology, Laarbeeklaan 103, B-1090 Brussels, Belgium d University of Antwerp, Department of Pharmaceutical Sciences, Laboratory of Pharmacognosy and Pharmaceutical Analysis, Universiteitsplein, B-2610 Antwerp, Belgium |
| Abstract: | Six flavonoids including two new flavones, luteolin 7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside), chrysoeriol-7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside) and a mixture of two pairs of diastereoisomeric flavonolignans, (±)-hydnocarpin 7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside)/(±)-hydnocarpin-D 7-O-(4″-O-(E)-coumaroyl)-β-glucopyranoside) with a 2:1 ratio were isolated from the whole plant of Mallotus metcalfianus Croizat, in addition to 10 known compounds. Their structures were evaluated on the basis of different spectroscopic methods, including extensive 1D and 2D NMR spectroscopy. Some extracts have moderate antimicrobial properties and interesting antiradical (DPPH) activity, as well as some compounds isolated from this species. Tannins were also identified in some active extracts. |
| Keywords: | Mallotus metcalfianus Croizat Euphorbiaceae Flavones Flavonolignans Antiradical activities |
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