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Managing and exploiting stress in the antibody factory
Authors:Cenci Simone  Sitia Roberto
Institution:Department of Biology and Technology, DiBiT, San Raffaele Scientific Institute, Universitá Vita-Salute San Raffaele, Milan, Italy.
Abstract:
Keywords:DRiPs  defective ribosomal products  ER  endoplasmic reticulum  ERAD  ER associated degradation  Ig  immunoglobulin  MM  multiple myeloma  PDI  protein disulfide isomerase  PI  proteasome inhibitors  RDP  rapidly degraded polypeptides  ROS  reactive oxygen species  UPR  unfolded protein response
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