Formation of closed vesicles from a simple phosphate diester. Preparation and some properties of vesicles of dihexadecyl phosphate |
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| Authors: | Renato A. Mortara Frank H. Quina Hernan Chaimovich |
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| Affiliation: | Group for Interfacial Studies (GIST) Instituto de Química, Universidade de São Paulo, Caixa Postal 20780, São Paulo, Brasil |
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| Abstract: | Upon sonication in water above 55°, dihexadecyl phosphate forms aqueous dispersions. Gel filtration, substrate entrapment and electron microscopic investigations indicate that these dispersions consist of closed vesicles possessing the characteristics of single bilayer liposomes. These dispersions are quite sensitive to the presence of salts. These wholly synthetic phosphate diester vesicles provide one of the simplest models for the mimicry of membrane and transport functions. |
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