Specific binding of the calcium-dependent regulator protein to brain membranes from the guinea pig期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Specific binding of the calcium-dependent regulator protein to brain membranes from the guinea pig

Authors:	André Vandermeers Patrick Robberecht Marie-Claire Vandermeers-Piret Jean Rathé Jean Christophe

Affiliation:	Department of Biochemistry, Université libre de Bruxelles, School of Medicine, Waterloo Boulevard 115; B-1000 Brussels, Belgium

Abstract:	The interaction of a calcium-dependent regulator protein (CDR) of brain adenylate cyclase (EC 4.6.1.1) with synaptic membranes from guinea pig brain was examined using ¹²⁵I-CDR as a tracer molecule. ¹²⁵I-CDR binding was reversible, saturable, and temperature sensitive. The same Ca²⁺ and Mg²⁺ dependence was observed for ¹²⁵I-CDR binding and for brain adenylate cyclase activation by CDR.

Keywords:	CDR EGTA ethyleneglycol-bis-(2-aminoethylether)-N,N′-tetraacetic acid
本文献已被 ScienceDirect 等数据库收录！