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Effect of experimental diabetes on ornithine decarboxylase activity of rat tissues
Authors:Milena Sochor  Najma Zaheer Baquer  John S. Hothersall  Patricia McLean
Affiliation:Courtauld Institute of Biochemistry, The Middlesex Hospital Medical School, London W1P 5PR, UK
Abstract:Measurements have been made of the activity of ornithine decarboxylase of liver, heart, kidney and brain in alloxan-diabetic and control rats. In all these tissues this enzyme had decreased markedly at four weeks after induction of diabetes. These results are discussed in relation to the hormonal control and cyclic nucleotide regulation of ornithine decarboxylase.
Keywords:ODC  ornithine decarboxylase (L-ornithine carboxylyase) (EC 4.1.1.17)  cAMP  adenosine 3′:5′-monophosphate  cGMP  guanosine 3′:5′-monophosphate
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