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Population genetic analysis of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China
Authors:Bo-feng Zhu  Guang Yang  Chun-mei Shen  Hai-xia Qin  Shuan-liang Fan  Li-bin Deng  Feng Chen  Li-ping Chen  Hong-dan Wang  Zhen-yuan Wang  Rudolf Lucas  Zhen-min Lian
Institution:1. Mobile post-doctoral station, Shaanxi Normal University, Xi’an, 710062, China
2. College of Life Sciences, Shaanxi Normal University, Xi’an, 710062, China
3. Department of Forensic Medicine, School of Medicine, Xi’an Jiaotong University, Xi’an, 710061, China
4. Vascular Biology Center, Medical College of Georgia, Augusta, GA, 30912, USA
5. Shaan’xi Blood Center, Xi’an, 710061, China
6. Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA, 30912, USA
7. Faculty of Basic Medical Science, Nanchang University, Nanchang, 330006, China
8. College of Life Sciences, Yanan University, Yanan, 716000, China
Abstract:In the present study, we investigated the genetic polymorphisms of 15 autosomal STR loci in the Russian population of northeastern Inner-Mongolia, China as well as its genetic relationships with other populations. DNA typing for 15 autosomal STR loci was performed on 148 randomly selected healthy individuals from the Russian population living in Eerguna, northeastern Inner-Mongolia. Allelic frequencies of these loci were calculated by direct counting. The genotype data of this Russian population was moreover compared to other populations using neighbor-joining method, as such constructing a phylogenic tree. A total of 143 alleles were found in the Russian population with corresponding allele frequencies in the range from 0.0034 to 0.5372. Among all the 15 loci, D18S51 had the highest polymorphism (PIC = 0.8632), whereas TPOX had the lowest (PIC = 0.5179). In the phylogenic tree, this Russian population has a close relationship with the populations of South Siberia and northeastern Asia. This study may increase our understanding of the genetic background of the Russian population in Eerguna, China as such providing useful information for anthropological research, forensic sciences as well as disease-association studies.
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