Molecular characterization of a cloned dolphin mitochondrial genome |
| |
Authors: | Šárka O Southern Peter J Southern Andrew E Dizon |
| |
Institution: | (1) Scripps Institution of Oceanography, Marine Biology Research Division, University of California, San Diego, A-002, 92093 La Jolla, California, USA;(2) Department of Immunology, Scripps Clinic and Research Foundation, 92037 La Jolla, California, USA;(3) National Marine Fisheries Service, Southwest Fisheries Center, NMFS, PO Box 271, 92038 La Jolla, California, USA;(4) Present address: Department of Biology, University of California, San Diego, Q-063, 92093 La Jolla, California, USA |
| |
Abstract: | Summary DNA clones have been isolated that span the complete mitochondrial (mt) genome of the dolphin,Cephalorhynchus commersonii. Hybridization experiments with purified primate mtDNA probes have established that there is close resemblance in the general organization of the dolphin mt genome and the terrestrial mammalian mt genomes. Sequences covering 2381 bp of the dolphin mt genome from the major noncoding region, three tRNA genes, and parts of the genes encoding cytochrome b, NADH dehydrogenase subunit 3 (ND3), and 16S rRNA have been compared with corresponding regions from other mammalian genomes. There is a general tendency throughout the sequenced regions for greater similarity between dolphin and bovine mt genomes than between dolphin and rodent or human mt genomes. |
| |
Keywords: | D-loop sequence Similarity blocks Sequence evolution Conservation of genome organization |
本文献已被 SpringerLink 等数据库收录! |
|