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Properties of histones on hydrophobic chromatography]
Authors:J Mizon  P H Corbisier  C Mizon-Capron  S Lagouge-Baras  G Biserte
Affiliation:Laboratoire de Biochimie, Faculté de Pharmacie, Rue du Professeur Laguesse, 59045 Lille Cedex et U 124 INSERM, BP 3567 Lille Cedex, France
Abstract:The hydrophobic chromatography on alkylated Sepharose allows to separate the histones into three groups which exhibit an increasing affinity for the support HI less than H2A-H2B less than H3-H4. In this fractionation procedure, the behaviour of the histones taken separately or pair-associated, is discussed in relation with the ability of these proteins to complex each other in vitro and in vivo.
Keywords:A qui toute correspondance doit être adressée.
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