Activation of glycogen synthetase and inactivation of phosphorylase kinase by the same phosphoprotein phosphatase期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Activation of glycogen synthetase and inactivation of phosphorylase kinase by the same phosphoprotein phosphatase

Authors:	F J Zieve W H Glinsmann

Institution:	Section on Physiological Controls, Laboratory of Biomedical Sciences, National Institute of Child Health and Human Development, Bethesda, Maryland 20014 USA

Abstract:	Purified rabbit muscle glycogen synthetase D phosphatase inactivates phosphorylase kinase. The inactivation is reversed by cyclic AMP-dependent protein kinase. It is postulated that the synthetase D phosphatase is a general phosphoprotein phosphatase which dephosphorylates proteins that are phosphorylated $in$ $vivo$ by the cyclic AMP-dependent kinase.

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