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Assignment of the gene for uroporphyrinogen decarboxylase to human chromosome 1 by somatic cell hybridization and specific enzyme immunoassay |
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| Authors: | H. de Verneuil B. Grandchamp Chantal Foubert Dominique Weil Cong Van N'Guyen Marie-Sylvie Gross Shigeru Sassa Y. Nordmann |
| Affiliation: | (1) Department of Biochemistry, Faculty of Medicine Xavier Bichat, Hospital Louis Mourier, F-92701 Colombes, France;(2) Unité de Recherche de Génétique Médicale, INSERM U12 (Pr. J. Frézal), Hôpital des Enfants Malades, 149 rue de Sèvres, F-75730 Paris Cedex 15, France;(3) Rockfeller University Hospital, 10021 New York, NY, USA |
| Abstract: | Summary A specific enzyme immunoassay of uroporphyrinogen decarboxylase was developed and applied to the detection of the human enzyme in man-rodent somatic cell hybrids. This method allowed to assign the gene for uroporphyrinogen decarboxylase to human chromosome 1. |
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