| 红曲霉液态发酵生产Monacolin K培养基的优化 |
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| 引用本文： | 汤卫华,乔长晟,贾士儒. 红曲霉液态发酵生产Monacolin K培养基的优化[J]. 生物加工过程, 2007, 5(2): 42-45 |
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| 作者姓名： | 汤卫华 乔长晟 贾士儒 |
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| 作者单位： | 1. 天津科技大学,天津市工业微生物重点实验室,天津,300222;天津现代职业技术学院,生物化工系,天津,300222
2. 天津科技大学,天津市工业微生物重点实验室,天津,300222 |
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| 摘 要： | 利用正交试验设计对红曲霉TQ-57发酵生产Monacolin K的摇瓶发酵培养基进行了初步研究。结果表明:Monacolin K的最适发酵碳源为甘油,最佳添加质量分数为14%,最适氮源为蛋白胨,最佳氮源质量分数为3%,培养基初始pH为6.5,培养周期为8 d,在此条件下Monacolin K产量可达27.75 mg/L。
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| 关 键 词： | 红曲霉 正交试验设计 液态发酵 |
| 文章编号： | 1672-3678（2007）02-0042-04 |
| 收稿时间： | 2006-11-09 |
| 修稿时间： | 2006-11-09 |
Optimization of the liquid culture medium for fermentation of Monacolin K by Monascus |
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| TANG Wei-hua,QIAO Chang-sheng,JIA Shi-ru. Optimization of the liquid culture medium for fermentation of Monacolin K by Monascus[J]. Chinese Journal of Bioprocess Engineering, 2007, 5(2): 42-45 |
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| Authors: | TANG Wei-hua QIAO Chang-sheng JIA Shi-ru |
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| Abstract: | Factors influencing the Monascus fuliginosus TQ-57 in producing Monacolin K were investigated by orthogonal experiment design.At the conditions of glycerol as carbon source at concentration of 14%,peptone as nitrogen source at concentration of 3%,medium pH of 6.5,and cultivation time of 8 days,the production concentration reached at 27.25 mg/L. |
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| Keywords: | Monacolin K |
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