Distribution of substance P-like immunoreactivity in the pedal ganglion of Mytilus galloprovincialis |
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Authors: | L Vitellaro-Zuccarello S De Biasi |
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Affiliation: | Dipartimento di Fisiologia e Biochimica Generali, Milano, Italy. |
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Abstract: | Nerve cell bodies and fibers displaying Substance P-like (SP-li) immunoreactivity have been identified in the pedal ganglia (PG) of Mytilus galloprovincialis. Most reactive neurons are small-sized, unipolar and are located in the ganglionic cortex. Positive fibers form a dense network in the neuropile and run parallel in the commissure and in the nerves and connective tracts. The positivity of the labelled elements to a monoclonal antibody indicates that SP-li substance of Mytilus contains a portion immunologically similar to the C-terminal pentapeptide responsible for the pharmacological activity of vertebrate SP. |
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