The expression of PS integrins in Drosophila melanogaster imaginal disc cell lines |
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Authors: | David John Peel Martin John Milner |
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Affiliation: | (1) Department of Biology and Preclinical Medicine, Bute Medical Buildings, University of St. Andrews, St. Andrews, Fife, KY16 9TS Scotland, UK;(2) Present address: Developmental Biology Center, University of California, Irvine, 92717 Irvine, CA, USA |
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Abstract: | Summary Drosophila imaginal disc cell lines show a characteristic pattern of aggregation in culture, which appears to be due to cell-cell rather than cell-substrate interactions. We have examined the distribution of PS integrins in wing and leg cell lines, and find that these integrin homologues are expressed preferentially in aggregates. Cell sheets, small cell clumps and chains of cells express antigen at points of cell-cell contact only. |
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Keywords: | Integrin Drosophila In vitro Imaginal disc |
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