Applications of LC-MS in the study of the uptake, distribution, metabolism and excretion of bioactive polyphenols from dietary supplements |
| |
Authors: | Barnes Stephen Prasain Jeevan K Wang Chao-Cheng Moore D Ray |
| |
Institution: | Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. sbarnes@uab.edu |
| |
Abstract: | Specific and quantitative analyses of the bioactive components and their metabolites in body fluids are essential to assess the interaction between groups of compounds in dietary supplements and preparations of psychoactives. Reverse-phase LC separations combined with tandem mass spectrometry provide the necessary specificity and sensitivity. In this paper, applications of these methods are described for the analysis of isoflavones, salvinorin A, synephrine isomers and their metabolites in serum, urine and aqueous humor. |
| |
Keywords: | Dietary supplements Phytochemicals Polyphenols Psychoactives Tandem mass spectrometry |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|