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Antibody suppression by zinc and nickel |
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| Authors: | S Mehrmofakham L Treagan |
| Institution: | (1) Department of Biology, University of San Francisco, 94117 San Francisco, CA |
| Abstract: | Rats were treated with zinc chloride and with nickel acetate 2 weeks prior to immunization withE. coli bacteriophageT-1; antibody titers to bacteriophageT-1 were reduced 500–2600-fold in metal-treated rats compared to titers found in untreated control animals. Examination of the effect of metal treatment on lymphocyte blastogenesis revealed a significant reduction in the number of blast cells in the spleens of metal-treated rats. |
| Keywords: | Zinc and antibody suppression in rats antibody suppression by zinc and nickel in rats blast cell transformation suppression by zinc and nickel immune suppression of antibodies by nickel and zinc nickel and antibody suppression in rats |
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