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1H, 13C and 15N resonance assignments of the periplasmic signalling domain of HasR, a TonB-dependent outer membrane heme transporter |
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| Authors: | Idir Malki Gisele Cardoso de Amorim Catherine Simenel Ada Prochnicka-Chalufour Muriel Delepierre Nadia Izadi-Pruneyre |
| Institution: | 1. Institut Pasteur, Unité de RMN des Biomolécules, Département de Biologie Structurale et Chimie, 28, rue du Dr Roux, 75724, Paris Cedex 15, France 2. CNRS, UMR 3528, 75015, Paris, France 3. Université Pierre et Marie Curie, Cellule Pasteur UPMC, 75015, Paris, France |
| Abstract: | TonB-dependent transporters (TBDTs) are bacterial outer membrane proteins that internalize nutrients such as vitamin B12, metal complexes, heme, some carbohydrates, etc. In addition to their transport activity, several TBDTs are also involved in a signalling cascade from the cell surface into the cytoplasm, via their periplasmic signalling domain. Here we report the backbone and side chain resonance assignments of the signalling domain of HasR, a TonB-dependent outer membrane heme transporter from Serratia marcescens as a first step towards its structural study. |
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