Endocytosis conducts the cell signaling orchestra |
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Authors: | Polo Simona Di Fiore Pier Paolo |
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Institution: | IFOM, Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20134 Milan, Italy. simona.polo@ifom-ieo-campus.it |
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Abstract: | Endocytosis is used by eukaryotic cells to regulate nutrient internalization, signal transduction, and the composition of the plasma membrane. However, a more complex picture is emerging, in which endocytic pathways integrate diverse signals, thereby contributing to a higher level of cellular and organismal organization. In this way, endocytosis and cell signaling are intertwined in many biological processes, such as cell motility and cell fate determination. |
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