Presence of cna, emp and pls genes and pathogenicity of methicillin-resistant Staphylococcus aureus strains |
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Authors: | Julianna Kurlenda Mariusz Grinholc Grzegorz Węgrzyn |
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Institution: | (1) Department of Biotechnology, Division of Molecular Diagnostics, Intercollegiate Faculty of Biotechnology, University of Gdańsk and Medical University of Gdańsk, Kładki 24, Gdansk, 80-822, Poland;(2) Department of Molecular Biology, University of Gdańsk, Kładki 24, 80-822 Gdansk, Poland |
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Abstract: | Methicillin-resistant strains of Staphylococcus aureus (MRSA) are important etiological factors responsible for hospital-acquired infections. The aim of this study was to analyze
the influence of the presence of emp, pls and cna genes on the pathogenicity of MRSA strains. The presence of these genes was tested by PCR in 302 MRSA strains isolated from
hospitalized patients and from carriers. For each tested gene, proportions of positive and negative strains were similar among
the infected patients and carriers. We did not find any obvious correlation between the presence of the three tested genes
and the infectivity of strains. Our results may also suggest that a lack of emp and presence of pls may correlate with reduced virulence of these strains. |
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Keywords: | MRSA Pathogenicity Virulence factors |
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