A new octopamine receptor class in locust nervous tissue, the octopamine 3 (OA3) receptor. |
| |
Authors: | T Roeder |
| |
Institution: | Universit?t Hamburg, Zoologisches Institut, Federal Republic of Germany. |
| |
Abstract: | The insect neuronal 3H-octopamine binding site represents a new type of octopamine receptor. This receptor has pharmacological features that are characteristic for all known octopamine receptors, but it is possible to distinguish this receptor class from all others using either agonists or antagonists. The quantitative determination of the pharmacological relationships to the other octopamine receptor classes could demonstrate greatest homology with both class 2 (OA2A and OA2B) receptors. Therefore, the neuronal octopamine receptor should be named a class 3 receptor (OA3). A new and simple classification scheme for octopamine receptors which enables classification of the new receptor class is established using antagonists. |
| |
Keywords: | |
|
|