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Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors
Authors:Bingham Alistair H  Davenport Richard J  Fosbeary Richard  Gowers Lewis  Knight Roland L  Lowe Christopher  Owen David A  Parry David M  Pitt Will R
Institution:UCB, Granta Park, Great Abington, Cambridge CB21 6GS, UK.
Abstract:The synthesis and structure-activity relationship of a novel series of aminopyrimidines are exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.
Keywords:
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