Calculation of the 3-D dose distribution surrounding a 103Pd stent |
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| Affiliation: | 1. Physik Department E21, Technische Universität München, D-85747 Garching, Germany;2. Heinz Maier-Leibnitz Zentrum (MLZ), Technische Universität München, D-85747 Garching, Germany;3. Peter Grünberg Institute (PGI-5) and Ernst-Ruska Centre for Microscopy and Spectroscopy with Electrons, Research Centre Jülich, D-52425 Jülich, Germany;4. nanoScale Biomagnetics SL, 50012 Zaragoza, Spain;5. Experimentalphysik V, Center for Electronic Correlations and Magnetism, Universität Augsburg, D-86159 Augsburg, Germany;6. Klinikum rechts d. Isar, Department of Radiooncology and HMGU München, CCG - Innate Immunity in Tumor Biology“, Technische Universität München, D-81675 München, Germany;1. Nankai University, Tianjin 300350, China;2. State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China;3. North China University of Water Resources and Electric Power, Zhengzhou 450045, China |
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| Abstract: | Purpose: This study was designed to assess the suitability of a 103Pd-implanted stent for use in intravascular brachytherapy. Materials and methods: A stent was modeled as a superposition of 201 identical struts and the EGS4/DOSRZ Monte Carlo code was used to calculate the dose distribution for each strut. To verify the simulation parameters, doses along the transverse axis of a Model 200 103Pd interstitial seed were calculated and compared to those calculated by the TG43 method. Results: Dose profiles within 1 mm of the stent's outer surface were heterogeneous and reflected the stent's structure. For a 2-mm outer-diameter 103Pd-implanted stent, ∼2.68×107 Bq were required to deliver 31.5 Gy in 28 days at a distance of 0.5 mm along the perpendicular bisector from the stent's outer surface. The Monte Carlo simulation of the 103Pd seed showed relative doses within 7% of the values calculated by the TG43 method. Conclusion: The dosimetry about a 103Pd-implanted stent suggests that the stent is suitable for use in intravascular brachytherapy. |
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