Plasmodium berghei: Specific stimulation of rat lymphocytes by soluble antigens released in vitro from infected erythrocytes |
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| Authors: | H Weissberger J Golenser DT Spira |
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| Institution: | Department of Protozoology and The Center for the Study of Tropical and Infectious Diseases, The Hebrew University-Hadassah Medical School, Jerusalem, Israel |
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| Abstract: | Soluble components released in vitro from rat erythrocytes parasitized with Plasmodium berghei have been shown to stimulate nonadherent spleen lymphocytes from rats convalescent from homologous infection. The active product is released from the infected erythrocytes either spontaneously during incubation, or as the result of artificial rupture of infected erythrocytes by freezing and thawing or sonication. This antigen produced precipitation lines with antiplasmodial antibodies from sera of convalescent and hyperimmune rats and from immunized rabbits. |
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| Keywords: | Protozoa parasitic Rat Antigens soluble Immunity cell mediated Lymphoblast transformation Suppressor cells |
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