| Abstract: | Using voltage clamping, changes in inward calcium current arising after the occurrence of postsynaptic currents were investigated in isolated neurons ofHelix lucorum. Inward calcium current was reversibly reduced during the formation of inhibitory or excitatory postsynaptic current, produced either by spontaneous activation of an unidentified interneuron or by stimulating the anal nerve. Application of serotonin to the neuronal cell body also reversibly suppressed calcium current. The possible cell mechanism of the changes under study and their putative physiological role are discussed.A. A. Bogomolete Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Translated from Neirofiziologiya, Vol. 18, No. 1, pp. 77–85, January–February, 1986. |
