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Mitosis in adult human Leydig cells
Authors:Prof. Dr. P. Amat  R. Paniagua  M. Nistal  A. Martín
Affiliation:(1) Department of Electron Microscopy, Universitary Clinical Hospital, Salamanca, Spain;(2) Department of Cytology and Histology, Faculty of Biology, Salamanca, Spain;(3) Department of Morphology, School of Medicine, Autonomous University of Madrid, Spain;(4) Departamento de Microscopía Electrónica, Hospital Clinico Universitario, 37007 Salamanca, Spain
Abstract:Summary The ultrastructural study of testicular biopsies from 87 adult men revealed mitosis in two mature Leydig cells, each from a different man. The men showed normal hormone levels and had received no previous chemotherapy or hormone treatment, nor had they been exposed to known toxic agents. The presence of mitotic Leydig cells suggests that differentiated Leydig cells may divide and contribute either to the increase in the number of Leydig cells or to the formation of multinucleate Leydig cells.This work was partially supported by a grant from the ldquoComisión Asesora de Investigación Científica y Técnicardquo, Madrid, Spain
Keywords:Leydig cell  Mitosis  Human testis
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