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Simply the right time to turn on insulin
Authors:Francesca M Spagnoli
Affiliation:Max Delbrück Center for Molecular Medicine (MDC), Berlin, Germany
Abstract:Recent research has made important progress in the directed differentiation of human pluripotent stem cells into insulin‐producing beta‐like cells in vitro. A new study published in this issue of The EMBO Journal reports that timely induction of NEUROG3 expression in pancreatic progenitors is a crucial checkpoint for generation of functional human beta cells.
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