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htSNPer1.0: software for haplotype block partition and htSNPs selection

Authors:	Keyue?Ding,Jing?Zhang,Kaixin?Zhou,Yan?Shen author-information" > author-information__contact u-icon-before" > mailto:sheny@ms.imicams.ac.cn" title=" sheny@ms.imicams.ac.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Xuegong?Zhang author-information" > author-information__contact u-icon-before" > mailto:zhangxg@tsinghua.edu.cn" title=" zhangxg@tsinghua.edu.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author

Affiliation:	(1) National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, 100005, China;(2) MOE Key Laboratory of Bioinformatics/Department of Automation, Tsinghua University, Beijing, 100084, China;(3) Chinese National Human Genome Center, Beijing, 100176, China

Abstract:	Background There is recently great interest in haplotype block structure and haplotype tagging SNPs (htSNPs) in the human genome for its implication on htSNPs-based association mapping strategy for complex disease. Different definitions have been used to characterize the haplotype block structure in the human genome, and several different performance criteria and algorithms have been suggested on htSNPs selection.

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