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Wnt5 signaling in vertebrate pancreas development |
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| Authors: | Hyon?J?Kim Jack?R?Schleiffarth Jose?Jessurun Saulius?Sumanas Anna?Petryk Shuo?Lin |
| Institution: | (1) Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA;(2) Department of Molecular, Cellular, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA;(3) Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA;(4) Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA |
| Abstract: | BackgroundSignaling by the Wnt family of secreted glycoproteins through their receptors, the frizzled (Fz) family of seven-pass transmembrane proteins, is critical for numerous cell fate and tissue polarity decisions during development. |
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