首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors
Institution:1. Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa;2. Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa;3. Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa;4. Centre for Metal-based Drug Discovery, Advanced Materials Division, Mintek, Randburg 2125, South Africa;1. Organic Research Laboratory, Department of Bioresources and Food Science, College of Life and Environmental Sciences, Konkuk University, Seoul 143 701, South Korea;2. Laboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany ASCR & Palacký University, Šlechtitelů 27, 783 71 Olomouc, Czech Republic;1. Departments of Discovery Chemistry and Molecular Technologies, 5 Research Parkway, Wallingford, CT 06492, USA;2. Virology, Bristol-Myers Squibb Research and Development, 5 Research Parkway, Wallingford, CT 06492, USA;3. Biocon-Bristol-Myers Squibb Research Center, Plot 2 & 3, Bommasandra Industrial Estate - Phase-IV, Bommasandra-Jigani Link Road, Bengaluru, Karnataka 560099, India;4. Department of Discovery Chemistry Synthesis, Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA;5. ViiV Healthcare, 36 East Industrial Parkway, Branford, CT 06405, USA;6. Assembly Biosciences, Inc. 331 Oyster Point Blvd, San Francisco, CA 94080, USA;1. Department of Organic Chemistry, Institute of Organic Chemistry, Catalysis and Petrochemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského Street 9, 812 37 Bratislava, Slovakia;2. Department of Microbiology and Virology, Faculty of Natural Sciences, Comenius University in Bratislava, Mlynská dolina, 842 15 Bratislava, Slovakia;3. CNRS-Université de Strasbourg (ECPM), UMR 7509, SynCat, 25 Rue Becquerel, 67087 Strasbourg Cedex 02, France;4. CNRS-Université de Strasbourg (ECPM), UMR 7509, COHA-lab, 25 Rue Becquerel, 67087 Strasbourg Cedex 02, France;1. Key Laboratory for Green Chemical Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430073, China;2. School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan 430073, China;1. Bio-Center, Gyeonggido Business & Science Accelerator (GBSA), Suwon 16229, Republic of Korea;2. Department of Biosystems and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea;3. Biological Genetic Resources Utilization Division, National Institute of Biological Resources (NIBR), Incheon 22689, Republic of Korea;4. College of Pharmacy, Dankook University, Cheonan 330-714, Republic of Korea;1. CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China;2. The National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 189 Guoshoujin Road, Shanghai 201203, China;3. School of Chemical Science and Technology, Yunnan University, Kunming 650091, China
Abstract:
Keywords:2-quinolones  Synthesis  Morita_Baylis-Hillman  Bioassay  HIV-1 integrase inhibitors
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号