Approaches for treatment of aortic arch aneurysm,a numerical study |
| |
| Institution: | 1. Department of Biomedical Engineering, Tel Aviv University and Stony Brook University;2. Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA;3. Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA;1. University of Maryland Baltimore School of Medicine, Department of Neurology, 110 S. Paca St, Baltimore, MD 21202, USA;2. IRCCS Fondazione Don Carlo Gnocchi ONLUS, Biomedical Technology Department, via Capecelatro 66, 20148 Milano, Italy;3. Politecnico di Milano, Department of Electronics, Information and Bioengineering, via Golgi 39, 20133 Milano, Italy;1. Department of Oral Cell Biology and Functional Anatomy, Academic Center for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands;2. MOVE Research Institute Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands;3. Biomechanics Section, Department of Mechanical Engineering, KU Leuven, Leuven, Belgium;4. Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands;1. INRIA Paris, 2 Rue Simone Iff, 75012 Paris, France;2. Sorbonne Universités, UPMC Univ. Paris 6, Laboratoire Jacques-Louis Lions, 75252 Paris, France;3. Medical R&D, WBL Healthcare, Air Liquide Santé International, 1 Chemin de la Porte des Loges, 78350 Les Loges-en-Josas, France;4. Department of Mechanical Engineering, Lafayette College, Easton, PA 18042, USA |
| |
| Abstract: | Aortic arch aneurysm is a complex pathology which requires coverage of one or more aortic arch vessels. In this study we explore the hemodynamic behavior of the aortic arch in aneurysmatic and treated cases with three currently available treatment approaches: Surgery Graft, hybrid Stent-Graft and chimney Stent Graft. The analysis included four models of the time-dependent fluid domains of aneurysmatic arch and of the surgery, hybrid and chimney endovascular techniques. Dimensions of the models are based on typical anatomy, and boundary conditions are based on typical physiological flow.The simulations used computational fluid dynamics (CFD) methods to delineate the time-dependent flow dynamics in the four geometric models.Results of velocity vectors, flow patterns, blood pressure and wall shear stress distributions are presented.The results delineate disturbed and recirculating flow in the aortic arch aneurysm accompanied with low wall shear stress and velocities, compared to a uniformly directed flow and nominal wall shear stress (WSS) in the model of Surgery graft. Out of the two endograft procedures, the hybrid procedure clearly exhibits better hemodynamic performances over the chimney model, with lower WSS, lower pressure drop and less disturbed and vortical flow regions. Although the chimney procedure requires less manufacturing time and cost, it is associated with higher risk rates, and therefore, it is recommended only for emergency cases. This study may shed light on the hemodynamic factors for these complications and provide insight into ways to improve the procedure. |
| |
| Keywords: | Thoraces aortic aneurysm Endovascular repair Stent-graft CFD ADINA |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
