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New lead compounds for brassinosteroid biosynthesis inhibitors
Authors:Min Y K  Asami T  Fujioka S  Murofushi N  Yamaguchi I  Yoshida S
Institution:The Institute of Physical and Chemical Research (RIKEN), Wako, Saitama, Japan.
Abstract:The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazoyl)butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.
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