Backbone assignment of human proliferating cell nuclear antigen |
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| Authors: | Ricardo Sánchez Daniel Torres Jesús Prieto Francisco J Blanco Ramón Campos-Olivas |
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| Institution: | (1) Structural and Computational Biology Programme, Spanish National Cancer Center (CNIO), C. Melchor Fernández Almagro 3, Madrid, 28029, Spain;(2) Structural Biology Unit, CIC bioGUNE, Bizkaia Technology Park, Building 801A, Derio, 48160, Spain |
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| Abstract: | PCNA is an essential factor for DNA replication, repair, chromatin metabolism, and effector of cell-cycle regulatory signals.
The assignment of backbone 1HN, 13Cα, 13CO, and 15N, and sidechain 13Cβ resonances of the human PCNA homotrimeric ring (∼90 kDa, 261 residues) is reported here. |
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| Keywords: | Sliding clamp PCNA DNA metabolism TROSY Deuterated protein |
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