Improvement of alignment accuracy utilizing sequentially conserved motifs |
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| Authors: | Saikat?Chakrabarti Nitin?Bhardwaj Prem?A?Anand Email author" target="_blank">Ramanathan?SowdhaminiEmail author |
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| Institution: | (1) National Centre for Biological Sciences (TIFR), Bangalore, 560065, India;(2) Department of Chemical Engineering, Indian Institute of Technology, Mumbai, India;(3) International Institute of Information Technology (MSIT), Hyderabad, India |
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| Abstract: | Background Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins
is central to several areas such as homology modelling, docking studies, understanding evolutionary trends and study of structure-function
relationships. In recent times, improvement of existing progressing programs and implementation of new iterative algorithms
have made a significant change in this field. |
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