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Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion |
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| Authors: | Martínez-Azorín Francisco Calleja Manuel Hernández-Sierra Rosana Farr Carol L Kaguni Laurie S Garesse Rafael |
| Institution: | Departamento de Bioquímica, Instituto de Investigaciones Biomédicas 'Alberto Sols' CSIC-UAM, Facultad de Medicina CIBERER ISCIII, Universidad Autónoma de Madrid, Madrid, Spain; Centro de Biologia Molecular 'Severo Ochoa' CSIC-UAM, Universidad Autónoma de Madrid, Madrid, Spain; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA |
| Abstract: | |
| Keywords: | apoptosis DNA polymerase γ Drosophila melanogaster mitochondria oxidative phosphorylation oxidative stress |
| 本文献已被 PubMed 等数据库收录！ | |