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Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?
作者姓名:Labib K  Diffley JF
摘    要:


Is the MCM2–7 complex the eukaryotic DNA replication fork helicase?
Labib K,Diffley JF.Is the MCM2–7 complex the eukaryotic DNA replication fork helicase?[J].Current Opinion in Genetics & Development,2001,11(1):64-70.
Authors:Labib K  Diffley J F
Institution:Chromosome Replication Laboratory, ICRF Clare Hall Laboratories, Blanche Lane, South Mimms, EN6 3LD, Hertfordshire, UK.labib@icrf.icnet.uk
Abstract:The MCM2-7 complex is essential for both the initiation and elongation phases of eukaryotic chromosome replication. There is some evidence that MCM2-7 proteins may act as a DNA helicase; at the same time, a variety of other DNA helicases have also been implicated in the replication of eukaryotic chromosomes.
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