Discovery,properties, and biosynthesis of pseudouridimycin,an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase |
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Authors: | Maffioli Sonia I Sosio Margherita Ebright Richard H Donadio Stefano |
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Institution: | 1.Naicons Srl, Viale Ortles 22/4, 20139, Milan, Italy ;2.Waksman Institute of Microbiology and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, 08854, USA ; |
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Abstract: | Journal of Industrial Microbiology & Biotechnology - Pseudouridimycin (PUM) is a novel pseudouridine-containing peptidyl-nucleoside antibiotic that inhibits bacterial RNA polymerase (RNAP)... |
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