On the presence of carnitine acetyl transferase in human platelets |
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Authors: | M Giret V R Villanueva |
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Institution: | (1) Institut de Chimie des Substances Naturelles, C.N.R.S., 91190 Gif-sur-Yvette, France |
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Abstract: | Summary The presence of carnitine acetyl transferase (E.C.2.3.1.7) activity has been found for the first time in human platelets.
The enzymic activity was measured by a radiometric method based on the separation of labelled acetylcarnitine and carnitine
on a cation exchange column. Carnitine acetyl transferase activity closely paralleled the activity distribution of the mitochondrial
marker carnitine palmitoyl-transferase. Contrary to the marker enzyme, human platelet carnitine acetyl-transferase is rather
thermosensitive: 60% of its activity is lost after 10 min when kept at 37°C. |
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Keywords: | |
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