脑电仿生电刺激对缺血性脑卒中失眠症患者睡眠质量的影响

摘要 目的：探讨脑电仿生电刺激对缺血性脑卒中失眠症患者睡眠质量的影响。方法：2018年1月到2019年12月选择在新疆医科大学第六附属医院诊治的缺血性脑卒中失眠症患者120例，根据随机数字表法分为研究组与对照组各60例。对照组给予常规药物治疗，研究组在对照组治疗的基础上给予脑电仿生电刺激治疗，治疗观察4 w，评定患者睡眠质量变化情况。结果：两组治疗后的匹斯堡睡眠质量指数量表（Pittsburgh Sleep Quality Index，PSQI）评分都显著低于治疗前（P<0.05），研究组评分也显著低于对照组（P<0.05）。治疗后研究组的总有效率为98.3 %，显著高于对照组的85.0 %（P<0.05）。研究组治疗后的左右椎动脉血流速度都显著高于治疗前（P<0.05），也显著高于对照组（P<0.05）。治疗后两组的Berg平衡量表(Berg balance scale，BBS)与巴氏(Barthel)评分显著高于治疗前（P<0.05），研究组评分也显著高于对照组（P<0.05）。结论：脑电仿生电刺激在缺血性脑卒中失眠症患者中的应用能改善睡眠质量，提高恢复平衡与日常生活功能，改善脑血流速度，从而提高治疗效果。

Effects of Electroencephalographic Biomimetic Stimulation on Sleep Quality in Patients with Ischemic Stroke and Insomnia

ABSTRACT Objective: To investigate the effects of electromyography on the sleep quality of patients with ischemic stroke and insomnia. Methods: From January 2018 to December 2019, 120 patients with ischemic stroke and insomnia who were selected for treatment in the sixth affiliated hospital of Xinjiang Medical University were divided into study group and control group with 60 cases each according to the random number table method. The control group were received conventional drug treatment, and the study group were given electroencephalographic biomimetic stimulation on the basis of the treatment of the control group. The treatment were observed for 4 weeks, and the changes of sleep quality were evaluated. Results: The Pittsburgh Sleep Quality Index(PSQI) scores of the two groups after treatment were significantly lower than those before treatment(P<0.05), and the study group scores were also significantly lower than the control group(P<0.05). The total effective rates of the study group after treatment were 98.3 %, which were significantly higher than that of the control group(85.0 %, P<0.05). The blood flow velocity of the left and right vertebral arteries in the study group after treatment were significantly higher than that before the treatment(P<0.05), and were also significantly higher than the control group(P<0.05). The Berg balance scale(BBS) and Barthel scores of the two groups after treatment were significantly higher than those before treatment(P<0.05), and the scores of the study group were also significantly higher than the control group(P<0.05). Conclusion: The application of electroencephalographic biomimetic stimulation in patients with ischemic stroke insomnia can improve the quality of sleep, improve the balance of recovery and daily life, improve the cerebral blood flow velocity, and thus improve the therapeutic effect.