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Development of the Bispecific Antibody in Fab-scFv Format Based on an Antibody to Human Interferon Beta-1 and Antibody to HER2 Receptor |
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| Authors: | Panina A. A. Toporova V. A. Rybchenko V. S. Balabashin D. S. Argentova V. V. Yakimov S. A. Solopova O. N. Aliev T. K. Dolgikh D. A. Sveshnikov P. G. Kirpichnikov M. P. |
| Affiliation: | 1.Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997, Moscow, Russia ;2.Moscow State University, 119991, Moscow, Russia ;3.Russian Research Center for Molecular Diagnostics and Therapy, 117149, Moscow, Russia ;4.Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, 115478, Moscow, Russia ; |
| Abstract: | Russian Journal of Bioorganic Chemistry - The development of new therapies for malignant tumors is an urgent task. Currently, the humanized antibody trastuzumab is considered the “gold... |
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