Reproducible reference frame for in vitro testing of the human vertebrae |
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| Authors: | Valentina Danesi Lorenzo Zani Axel Scheele Francesco Berra Luca Cristofolini |
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| Affiliation: | 1. Laboratory for Medical Technology, Rizzoli Orthopaedic Institute, Bologna, Italy;2. Department of Industrial Engineering, School of Engineering and Architecture, University of Bologna, Viale Risorgimento, 2, 40136 Bologna, Italy;3. Department of Biomedical Engineering, Delft University of Technology, Delft, The Netherlands |
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| Abstract: | Definition of an anatomical reference frame is necessary for in vitro biomechanical testing. Nevertheless, there is neither a clear recommendation, nor consensus in the literature concerning an anatomical reference frame for in vitro testing of the human vertebrae. The scope of this work is to define a reference frame for the human vertebrae for in vitro applications. The proposed anatomical reference frame relies on alignment of well-defined points on the endplates, and on two landmarks on the posterior wall. The repeatability of the proposed alignment procedure has been tested in vitro by 5 operators, on 7 specimens. Furthermore, the feasibility and repeatability of the proposed procedure was assessed in silico, using CT-scans of the same specimens. |
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| Keywords: | Human vertebrae Thoraco-lumbar spine Vertebral body Anatomical reference frame Mechanical in vitro testing In vitro landmarks |
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